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Pantomerican

20 mg


Product Classification

  • Type: Proton Pump Inhibitor (PPI) – gastroenterology product.

  • Drug Category: Anti-ulcer medicine; reduces stomach acid.

  • Therapeutic Class: Gastroprotective agent used in acid-related disorders.

Active Ingredient and Composition

  • Pantoprazole Sodium Sesquihydrate equivalent to 20 mg Pantoprazole.

  • Excipients: stabilizers, fillers, and coating agents (details as per leaflet).

  • Formulation: Enteric-coated tablets to ensure release in the intestine, preventing degradation by gastric acid.

Mechanism of Action

  • Selectively inhibits the H+/K+-ATPase enzyme system in gastric parietal cells.

  • Suppresses final step of acid production in the stomach.

  • Provides long-lasting reduction of gastric acid secretion.

  • Promotes healing of erosions, ulcers, and esophagitis caused by excess acid.

Indications and Benefits

  • Primary Indications:

    • Gastroesophageal reflux disease (GERD).

    • Erosive esophagitis.

    • Zollinger-Ellison syndrome and other hypersecretory conditions.

  • Secondary Benefits:

    • Short-term relief of heartburn, acid reflux, and stomach discomfort.

    • Promotes healing of stomach and duodenal ulcers.

    • Protects the stomach in patients taking long-term NSAIDs.

Dosage and Administration

  • Standard Adult Dose: 20 mg once daily, taken before a meal.

  • Duration: Typically 2–8 weeks depending on condition; doctor may extend if needed.

  • Administration: Swallow whole with water; do not crush or chew.

  • Special Populations:

    • Use with caution in patients with severe liver impairment.

    • Dose adjustment usually not required in renal impairment.

Contraindications and Warnings

  • Do not use in patients with known hypersensitivity to pantoprazole or other PPIs.

  • Avoid use with atazanavir and certain HIV medicines (interaction reduces efficacy).

  • Long-term use may increase risk of:

    • Vitamin B12 deficiency.

    • Magnesium deficiency.

    • Bone fractures (osteoporosis-related).

  • Pregnancy/Lactation: Use only under medical advice.

  • Not recommended in children under 12 years without specialist guidance.

Possible Side Effects

  • Common: Headache, diarrhea, nausea, abdominal pain, flatulence.

  • Rare: Rash, dizziness, joint pain.

  • Very rare: Severe allergic reactions, kidney inflammation, visual disturbances.

  • Report any persistent or unusual side effects to a healthcare provider.

Packaging and Presentation

  • Pantomerican 20 mg Tablets: Blister packs inside carton.

  • Available pack sizes: Vary depending on market regulations (commonly 14 or 28 tablets).

  • Clearly labeled with dosage, batch number, and expiry date.

Storage and Shelf-Life

  • Store below 25°C, away from moisture and sunlight.

  • Keep tablets in original blister until use.

  • Shelf life: Typically 24–36 months from manufacturing date.

  • Keep out of reach of children.

Manufacturer and Brand

  • Manufacturer: Paxal Pharma (contract manufacturing with certified GMP facilities).

  • Distributor/Marketer: Paxal Pharma, Egypt.

  • Brand Positioning: Doctor-recommended, high-quality proton pump inhibitor for acid-related diseases.

  • Core Values: Innovation, patient safety, reliable pharmaceutical care.

Unique Points (USPs)

  • Proven efficacy in acid suppression and ulcer healing.

  • Once-daily dosing for patient convenience.

  • Trusted brand marketed by Paxal Pharma, known for innovation and patient care.

  • High-quality standards: Complies with international GMP.

  • Affordable and accessible in pharmacies across Egypt.

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